Abstract
Benzodiazepine and GABA binding sites in the rat retina are influenced by a vitamin A-free diet. In rats fed a vitamin A-free, the total number of [ 3H]GABA and [ 3H]diazepam binding sites was markedly higher than in rats given a balanced diet. No differences were found in the apparent affinities of [ 3H]GABA and [ 3H]diazepam for their specific binding sites. The results suggest that GABA and benzodiazepine binding sites have a role in the function of the retina.
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