Abstract

Context Resistance exercise training has recently been considered as an effective type of training to increase energy metabolism and insulin sensitivity. However, mechanisms of the resistance training-induced improvements in energy metabolism and insulin sensitivity have not been fully understood. Zinc-α2-glycoprotein (ZAG), which is a novel adipokine, has beneficial effects on energy metabolism and insulin sensitivity. Objective We investigated the effect of a single bout of resistance exercise on the ZAG concentration. Methods Nine healthy men were enrolled. They performed a single bout of resistance exercise (bench press and leg press) consisting of 10 repetitions of five sets at 70% of maximum strength with 90-s rests in between sets. Blood samples were obtained before and after acute resistance exercise to measure the ZAG concentration. Results The serum ZAG concentration significantly increased following acute resistance exercise. Conclusion This result suggests that a single bout of resistance exercise may enhance the ZAG concentration.

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