Abstract

ObjectiveTo evaluate the effect of the MD.2 Personal Medication System (MD.2) on patient medication adherence and refill persistence. DesignOpen noncontrolled case series. SettingCommunity pharmacy. PatientsThree patients with a documented history of poor medication adherence and persistence. interventionMD.2 placed in patients’ homes for 3months. Main outcome measuresMedication adherence (doses taken at prescribed times) and persistence (refills obtained at correct times) assessed before and after installation of MD.2. ResultsInstallation of MD.2 resulted in medication adherence rates of greater than 99% in all three patients. Refill persistence rates improved in both patients who needed refills during the study period. Missed doses and other problems were mostly due to caregiver error in filling or programming MD.2. ConclusionThe MD.2 Personal Medication System had a positive effect on medication adherence and persistence in these three patients. Training and selection of caregivers may be especially important for effective use of the machine. Larger studies will be needed to validate these results.

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