Abstract

In this study we took advantage of known impact of strontium (Sr) on bone metabolism and evaluated the effect of sustained supply of Sr on local bone healing. Four distinct surface modifications prepared by a magnetron co-sputtering process with different Sr-release profiles were investigated in a rat model. Four weeks after surgery bone blocks with implants (1.1mm diameter, 5mm length), which were inserted bicortically in the femoral shaft, were harvested and subsequently evaluated via histomorphology.

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