Abstract
Sevoflurane (2,2,2-trifluoro-1-[trifluoromethyl]ethyl fluoromethyl ether or C4H3F7O), with a molar mass 200.055 g/mol, also called fluoromethyl, is a highly fluorinated methyl isopropyl ether with general anesthetic property, available for clinical practice for about 30 years. Sevoflurane is a sweet-smelling, non-flammable and it is used for induction and maintenance of general anesthesia. Together with desflurane, it is replacing isoflurane and halothane in modern anesthesiology. Propofol (2,6-diisopropylphenol or C12H18O), with a molar mass 178.271g/mol is an alkylphenol derivative formulated for induction and maintenance (in some cases) of general anesthesia, sedation and hypnosis and acting as an intravenous anaesthetic drug, having largely replaced sodium thiopental because recovery from propofol is more rapid and clear.
Highlights
Sg/emvoofll,uarlasnoec(a2ll,e2d,2f-lturioflruoomroe-t1h-[ytlr,iifsluaohroigmhleytfhluylo]reitnhaytlefdlumoreotmhyeltihsoylpertohpeyrloerthCe4Hr w3Fi7tOh)g,ewniethraal molar mass 200.055 anesthetic property, available for clinical practice for about 30 years
The study exclusion criteria were the following: - longer than estimated procedures where the anesthesia was prolonged by general anesthesia with endotracheal intubation; - patients aged less than 12 months, - children above 3 years old - emergency patients who received spinal anesthesia without sedation, on the grounds of a full stomach
About a third of the anesthesias performed within two years for scheduled or emergency surgeries on pediatric patients in the children’s hospital where the study was conducted were spinal anesthesias
Summary
Sg/emvoofll,uarlasnoec(a2ll,e2d,2f-lturioflruoomroe-t1h-[ytlr,iifsluaohroigmhleytfhluylo]reitnhaytlefdlumoreotmhyeltihsoylpertohpeyrloerthCe4Hr w3Fi7tOh)g,ewniethraal molar mass 200.055 anesthetic property, available for clinical practice for about 30 years. The present study provide evidence for further dates to develop and optimize the method of sedation which combining with spinal anesthesia to be safe and offer a comfortable awakening for all the pediatric patients. To intravenous maintenance sedation with Propofol is likely to be the solution to prevent emerge delirium in younger children undergoing spinal anesthesia and it’s worth studying
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