Abstract

Objective To investigate the clinical effect of racecadotril granules combined with Saccharomyces boulardii in the treatment of infants with moderate and severe acute watery diarrhea. Methods 90 infants with moderate and severe acute watery diarrhea in our hospital from April 2015 to August 2016 were selected as the research object, and randomly divided into the control group and the observation group, 45 cases in each group. The control group was treated with racecadotril granules, and the observation group was treated with racecadotril granules combined with Saccharomyces boulardii. Observed the treatment effect of diarrhea of two groups, monitored the dehydration time, diarrhea frequency in 24 h, and adverse reactions of two groups. Results The total effective rate (97.78%) in the observation group was significantly higher than that in the control group (80.00%), with statistically significant difference between the two groups (P 0.05). Conclusion Racecadotril granules combined with Saccharomyces boulardii in the treatment of infants with moderate and severe acute watery diarrhea has reliable clinical curative effect, with good control effect on diarrhea and high clinical safety, is worth popularizing. Key words: Diarrhea; Racecadotril granules; Saccharomyces boulardii

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