Effect analysis of neuroendoscopy combined with neuronavigation in the treatment of hypertensive intracerebral hemorrhage

Abstract

Objective To investigate the efficacy of neuroendoscopy combined with neuronavigation in the treatment of hypertensive intracerebral hemorrhage (HICH). Methods A retrospective analysis was conducted on 96 patients with HICH who underwent treatment at Department of Neurosurgery, the Affiliated Dalian Central Hospital of Dalian Medical University from January 2015 to January 2017. All cases were divided into endoscopic navigation group (n=44) and microscopy group (n=51) based on the treatment method. The endpoints including hematoma clearance rate, intraoperative blood loss, operation time, postoperative hospitalization and hospitalization expenses were analyzed and compared between the 2 groups. The Glasgow outcome scale (GOS) was used for assessment at a 6-month follow-up. Results Hematoma clearance rate in endoscopic navigation group was higher than that in microscopy group (91.5±6.0 % vs. 83.7±6.8 %, P<0.001), while intraoperative blood loss(74.1±14.0 ml vs. 224.9±32.6 ml), operation time(69.6±13.7 min vs.128.2±28.4 min), postoperative hospitalization(12.4±2.8 d vs.18.3±2.4 d), and hospitalization expenses(38 600±9 600 yuan vs. 52 300±11 200 yuan) in endoscopic navigation group were significantly lower than those in microscopy group (all P<0.001). At the 6-month follow-up, the score of GOS in endoscopic navigation group was significantly better than that in microscopy group (P=0.029). Conclusion Treatment of HICH using neuroendoscopy combined with neuronavigation seems to be featured with less trauma, good efficacy, good prognosis and low costs, which is thus worth being applied and promoted in clinical practice. Key words: Natural orifice endoscopic surgery; Intracranial hemorrhage, hypertensive; Neurosurgical procedures; Neuronavigation; Treatment outcome