Abstract
The mesocarp of Babassu (Orbignya phalerata) has been used in experimental studies trying to check its pro-inflammatory effect. To analyse comparatively the histological changes made by the water extract of Babassu in skin surgical wounds. Sixty Wistar adult male rats were used. The experimental procedure was a circle skin incision of 2 cm in diameter made with a metal punch. After this procedure done in all animals, they were randomized in two groups of 30. In the control group, the phytotherapeutic agent wasn't used but saline solution. In the experimental group, the water extract of Orbignya phalerata was used in the cut sites. All animals were followed and killed after seven, 14 and 21 days. Comparative histological analysis was made among the groups. In the microscopic view, a significant reepitelization effect on the healing process of the experimental group in relation to the control group in the 7th and 14th days, was recognized. The use of the mesocarp of Orbignya phalerata in skin surgical wounds contributed positively in the healing process in rats.
Highlights
The mesocarp of Babassu (Orbignya phalerata) has been used in experimental studies trying to check its pro-inflammatory effect
Os efeitos no 7o, 14o e 21o dias em ambos os grupos nas variáveis numéricas, foram calculados pelo teste da ANOVA com dois fatores de interação entre si
AEfeito do uso tópico do extrato aquoso de Orbignya phalerata (Babaçu) na cicatrização de feridas cutâneas - estudo controlado em ratos
Summary
Foram estudados 60 ratos (Rattus novergicus albinus, Rodentia mammalia), da linhagem Wistar, adultos, machos, com idade média de 45 dias pesando entre 129 a 234 gramas, adquiridos no Biotério Central de Campinas, São Paulo (UNICAMP), Centro Multidisciplinar para Investigação Biológica (CEMIB) e transferidos para o Laboratório de Pesquisa do Departamento de Fisiologia e Farmacologia do Centro de Ciências Biológicas e da Saúde da Universidade Federal do Maranhão.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
