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Abstract
Since the Warburg's method was established for the investigation of metabolism in the irradiated tissue. many reports have been published, but the results are not always in agreement.As to the cause of the discordance, it can be considered that various may secondarily be produced during irradiation. In the present experiments, effects of roentgen irradiation on Yoshida sarcoma, which is wandering single cell, were investigated with the Warburg's manometer, and the following results were obtained.1. The respiration of Yoshida sarcoma was slightly inhibited by irradiation in adose of 5700 r (11%). In the case of endogenous respiration, increase was sometimes observed (below 600 and above 950 in 1 mm3).2. The metabolism of aerobic sugar decomposition was more affected than respiration (24.6%) 3.Anaerobic sugar decomposition was most sensitive, being remarkably diminished with change in the, dosage of irradiation.
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