Abstract
In approximately 15% of homosexual men, their phenotype is associated to the fraternal birth order. Older biological brothers induce in their mothers anti-male factors (antibodies) that interfere the brain maleness development of younger fetuses. This effect is seldom seen in non-right-handed men and is not seen in women. The influence of older siblings is seen in their sex ratio (SR). In contradiction with previous hypothesis, significant heterogeneities of SR have been found among older siblings of males or females, right or non-right-handed and homo or heterosexual individuals. This can only be understood as if the findings among homosexuals were part of a general mechanism of fetus-maternal tolerance-rejection processes of placental mammals. We found, in relation to ABO and Rh systems and sex, that embryos with genes different from those of their mothers, induced better pregnancies and maternal tolerance than embryos similar to their mothers. Assuming that homo or heterosexuality and right or non-right-handedness behave similar to ABO or Rh alleles, the author provides a speculative interpretation of these results. Homosexual women and especially if they are non-right-handed, are preceded by siblings with a high SR (maternal environment with anti-female or pro-male factors); then lesbianism or non-right-handedness may induce tolerance to be a woman in such anti-female environment. Non-right-handedness could induce tolerance for anti-male factors of mothers, thus preventing the production of gays in a pro-male maternal environment, but leading to the production of non-right-handed gays in anti-male maternal environments. Several new hypotheses and interpretations merge from this new proposition. Also, complete sexual orientation could be acquired after birth.
Highlights
In approximately 15% of homosexual men, their phenotype is associated to the fraternal birth order
En 1980 descubrimos que los hermanos menores tendían a ser diferentes en sus genotipos Rh a sus hermanos previos lo que implicaba que las madres de un genotipo Rh, tenían menos progenie de ese genotipo en los embarazos sucesivos, y más de otros genotipos distintos a los de ellas aunque fueran incompatibles[20,21,22]
Los genes involucrados en producir el fenotipo no-diestro podrían, en cierto contexto genómico, ocultar al sistema inmune de la madre, la masculinidad del cerebro del embrión por la inducción de tolerancia en estos fenotipos, por estar protegidos de la acción inmune de la madre, o por interacciones genéticas complejas que cambian molecularmente los fenotipos
Summary
Prenatal maternal mnemonic effects on the human neuro-psychic sex. A new proposition from fetus-maternal tolerance-rejection. In contradiction with previous hypothesis, significant heterogeneities of SR have been found among older siblings of males or females, right or non-right-handed and homo or heterosexual individuals This can only be understood as if the findings found among homosexuals were part of a general mechanism of fetus-maternal tolerance-rejection processes of placental mammals. Afirmando la génesis neural prenatal del factor predisponente a la homosexualidad masculina se constató que este efecto se da en mucho menor grado en varones no-diestros[12,14]; a pesar que, los varones tienen mayor no-dextralidad (no usaremos dextrismo) que las mujeres y los homosexuales masculinos (gays) o femeninos (lesbianas) tienen más que los heterosexuales respectivos[15,16]. Los genes involucrados en producir el fenotipo no-diestro podrían, en cierto contexto genómico, ocultar al sistema inmune de la madre, la masculinidad del cerebro del embrión por la inducción de tolerancia en estos fenotipos, por estar protegidos de la acción inmune de la madre, o por interacciones genéticas complejas que cambian molecularmente los fenotipos
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