Abstract
ObjectiveTo study on isolated kidney perfusions by means of a self-designed computer-controlledorgan perfusion system the hydrodynamic and biochemical effects of two types of pumps: a self-designedvacuum powered tubular pump and a classical roller pump. Basic ProceduresExperimental study performed on 12 right mini-pig kidneys. After transperitonealbilateral nephrectomy, organs are perfused with Eurocollins solution in a randomised manner with one typeof pump. The system records continuously perfusion pressure, flow and renal resistance. ResultsMedium renal vascular resistance was significantly lower in vacuum powered tubular pumpperfusions. LDH level in the solution showed correlation with perfusion flow. ConclusionsVacuum powered tubular pump increases renal flow and lowers renal vascular resistancesignificantly in comparison to roller pump. LDH level in the solution is related to good-quality hydrodynamicperfusion parameter values.
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