Efecto desorbedor del metanol en la membrana celular

Abstract

The interaction of ethanol on the cellular membrane inhibits the interaction with membrane proteins or cellular receptors. Ethanol and other small alcohols are natural surfactants of aqueous/organic interfaces, and also affect the cellular membrane stressing it mechanically, and inhibit the natural adsorption of terminal groups at the aqueous/organic interface. In this work we show how methanol inhibits the adsorption of terminal groups even at very small concentrations. As methanol concentration increases in the aqueous phase, the interfacial tension decreases, showing additional stress over the cellular membrane.