Efecto del tratamiento con descontaminación digestiva selectiva en la mortalidad y la aparición de resistencia bacteriana en los pacientes ingresados en Unidades de Cuidados Intensivos

Abstract

PDMS (polydimethylsiloxane) has provided number of advantages in recent years has its applications in drug delivery system, dry electrodes and other microfluidic applications. PDMS has also gained its importance as it is easy to prepare and also biocompatible. In this work the PDMS is made to PDMS solid by processing the powder and the material is characterized using SEM (Scanning Electron Microscopy) and Raman Analysis. The characterizations were tested to prove the biocompatibility of the PDMS by carrying the tests in normal sample and sterilized sample. The conductivity of the material was studied for different proportion of binding agent used. Simulations were carried in COMSOL Multiphysics to study the relation between volume flow rate, velocity magnitude and pressure drop in the PDMS micro channel. The simulation results showed the linear relations between the studied variables. The results of the characterization showed the prepared PDMS was in optimum condition and can be used for biomedical applications. The PDMS hydrophilic nature was reduced after preparing the PDMS solid so that it can be coated with metals for electrode and micro channel applications