Efecto de la sinergia de los factores de riesgo para cáncer de mama en mujeres de la ciudad de Veracruz

Abstract

Introduction and objectivesBreast cancer (BC) is the most common neoplasm in women worldwide. The World Health Organisation estimates that 30% of deaths due to BC are associated with lifestyle factors. In Mexico there is an obesity epidemic, which favours the appearance of hypertension and diabetes mellitus type 2 (DM2). However, there have been few studies of the prevalence and clinical contribution of this triad in the development of BC and its interaction with known risk factors. Materials and methodsWe analysed the association of obesity, hypertension and DM2, and risk factors for BC (reported in the clinical files of women with and without a diagnosis of BC in Hospital N.° 71 of the Mexican Institute of Social Security) and their proportional weight, with the presence or absence of a BC diagnosis. ResultsAmong the recognised risk factors for BC, only a hereditary family history and smoking were associated with a diagnosis of BC. Metabolic diseases showed no differences. However, the proportional weight of all the variables was statistically significant in the group with BC. ConclusionsThere is a need to modify the classical view that clinical factors per se determine the development of BC. Studies are needed that analyse the interrelation between risk factors and other disorders that have become highly prevalent in the population.