Abstract
Previous studies indicated that heroin abuse would result in abnormal functional organization of the brain. However, studies of heroin abuse- related brain dysfunction are scarce. The purpose of the present study was to investigate heroin effects on brain function by studying relationships between Electroencephalograph (EEG) spectral power and heroin abuse. The resting EEG signals were acquired from 15 male heroin dependent group and 15 male control group. The differences in the EEG components of each group were evaluated using the statistical Mann-Whitney examination and Davis Bouldin Index. The results show that heroin dependent group has an attenuated relative beta-2 power compared with other EEG frequency sub bands. Nevertheless, the results indicate heroin dependent group have an increase of power spectrum density for theta at all locations, as well as delta in the temporal, frontal and central areas compared with control group. Compared to control group, the heroin dependent group decreased its spectral power more than the control group in all three alpha bands. The present findings using the Davis Bouldin Index provide evidence that alpha-3 band in the FZ channel is more affected by heroin abuse than other frequency sub bands.
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