Abstract
EEG topography correlates of severity and type of Alzheimer type dementia (DAT) have been studied in 21 senile dementia (SD), and in 18 Alzheimer disease (AD) patients, as well as in 15 mentally normal elderly persons. EEG maps in SD and AD patients differed from that in normals by increase of theta-delta EEG spectral power, and by suppression of alpha band power, more pronounced in AD than in SD patients, especially, in the left hemisphere. AD and SD patients also showed different EEG topography dynamics with increase in degree of cognitive functions impairment assessed by MMSE. Results obtained are in good concordance with data on metabolism and local cerebral blood flow decrease, and on cognitive deficiencies in different clinical forms of DAT.
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