EEG Background Activity and Anticonvulsant Drugs

J Gordon Millichap

doi:10.15844/pedneurbriefs-9-5-8

Abstract

The effects of antiepileptic drugs (AED) on EEG background activity in 37 newly treated children with epilepsy were examined at the Departments of Pediatrics, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama City, Japan.

Highlights

EEG BACKGROUND ACTIVITY AND ANTICONVULSANT DRUGS The effects of antiepileptic drugs (AED) on EEG background activity in newly treated children with epilepsy were examined at the Departments of Pediatrics, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama City, Japan
Following 3 to 6 months of AED therapy, the EEG slowing was increased in 23 taking carbamazepine for partial seizures and reduced in the 14 treated with valproic acid for generalized seizures
The role of ictal or continuous epileptogenic discharges (I/CEDs), recorded during intraoperative electrocorticography (ECoG), in the planning of surgical resection for patients with cortical dysplastic lesions (CDyLs) and intractable partial seizures was evaluated at the Montreal Neurological Institute, the Epilepsy Surgery Program, Porto-Alegre, Brazil, and the Chonbuk National Hospital, Chonju, Korea

Summary

Introduction

The role of ictal or continuous epileptogenic discharges (I/CEDs), recorded during intraoperative electrocorticography (ECoG), in the planning of surgical resection for patients with cortical dysplastic lesions (CDyLs) and intractable partial seizures was evaluated at the Montreal Neurological Institute, the Epilepsy Surgery Program, Porto-Alegre, Brazil, and the Chonbuk National Hospital, Chonju, Korea. EEG BACKGROUND ACTIVITY AND ANTICONVULSANT DRUGS The effects of antiepileptic drugs (AED) on EEG background activity in newly treated children with epilepsy were examined at the Departments of Pediatrics, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama City, Japan. Compared to 46 age-matched healthy controls, the EEGs in children with epilepsy, before AED therapy, showed significant slowing.

Results

Conclusion