Abstract

The ECHELON-1 trial (NCT01712490) demonstrated superior progression-free survival for brentuximab vedotin plus doxorubicin, vinblastine, and dacarbazine (A+AVD) versus doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) in patients with frontline stage III/IV Hodgkin lymphoma with a median follow-up of 2 years and superior overall survival (OS) with a median follow-up of 6 years. The objective of this study was to compare the long-term survival extrapolations using trial data from early vs late datacuts.

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