Abstract

Hyperkalemia most commonly develops in patients with heart failure (HF) or chronic kidney disease (CKD). Sodium zirconium cyclosilicate (SZC) is a new selective potassium (K+) binder for the treatment of hyperkalemia. The aim of this study was to evaluate the cost-effectiveness of SZC versus usual care (consisting of calcium polystyrene sulfonate (CPS), lifestyle interventions, RAASi modifications, etc.) for the treatment of hyperkalemia among HF and CKD patients in China.

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