Abstract

Nadofaragene firadenovec (awaiting regulatory approval) and pembrolizumab are bladder-sparing alternatives for treating Bacillus Calmette–Guérin (BCG)-unresponsive, high-risk non-muscle invasive bladder cancer (NMIBC). Cost-utility and value of information (VOI) analyses of these treatments, compared with a hypothetical treatment comparator based on approved and investigational therapies, were conducted from a United States health system perspective.

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