Abstract

Adrenomyeloneuropathy (AMN) is the most common manifestation of X-linked adrenoleukodystrophy (X-ALD), a rare neurodegenerative disease caused by mutations in ABCD1, featuring progressive myeloneuropathy, spastic paraparesis, sensory ataxia, loss of mobility, incontinence, and sexual dysfunction. Presentation, onset and clinical manifestations vary between men and women. This study sought to quantify for the first time the impact of AMN on healthcare costs in commercially insured adults, both male and female, in the US.

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