Abstract

IgA nephropathy (IgAN) is a progressive autoimmune disease caused by an accumulation of immunoglobulin A in the kidneys. Complications can include the development of chronic kidney disease (CKD) and early end stage renal disease which may result in early death. The NefIgArd trial (NCT03643965) demonstrated favorable results for targeted release formulation (TRF)-budesonide compared to placebo for the treatment of primary IgAN. This study aims to assess the budget impact of introducing TRF-budesonide as a novel oral treatment for adult patients with primary IgAN in the United States.

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