Abstract

Nivolumab is the first immuno-oncology drug to demonstrate statistically significant improvement in disease-free survival for the adjuvant treatment of patients with muscle-invasive urothelial carcinoma (MIUC), who are at high risk of recurrence after undergoing radical resection, and who are at high risk of recurrence, compared to placebo (Checkmate 274). The objective of this study was to assess the cost-effectiveness of nivolumab vs surveillance, a proxy of placebo, in MIUC for patients with tumour cell PD-L1≥1% (expressed as tumor proportion score) in Greece.

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