Abstract

The Brazilian Private Health Care Sector has first-line and second-line metastatic gastric cancer (mGC) treatment options using traditional chemotherapy and targeted therapy. Recently, trifluridine and tipiracil hydrochloride (FTD/TPI) was approved in the third-line treatment and is the only treatment option to this subgroup of patients. Our objective was to evaluate the cost-effectiveness of FTD/TPI in mGC patients, including gastroesophageal junction adenocarcinoma, who have received at least two prior therapies for metastatic disease and are eligible for third-line treatment, from the perspective of private health care sector in Brazil.

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