Abstract

To examine potential cost-effectiveness of Alzheimer’s disease-modifying therapies (DMTs) of different treatment durations. BACKGROUND: Clinical trial results suggest the disease-modifying impact of a new class of anti-amyloid monoclonal antibodies. Optimal treatment duration is uncertain due to limited follow-up in clinical trials. A recent economic analysis of the first such agent approved questioned the economic value of treatments that slow progression of early symptomatic Alzheimer’s disease (AD) to more advanced states.

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