Abstract

There are limited real-world data on fremanezumab, a fully-humanized monoclonal antibody (mAb; IgG2Δa) that selectively targets calcitonin gene-related peptide (CGRP), in patients with prior exposure to other CGRP pathway-targeted mAbs such as erenumab. A US retrospective claims database study evaluated migraine-related healthcare resource utilization (HCRU) and costs for patients initiating fremanezumab treatment with common comorbidities, acute medication overuse (AMO), or difficult-to-treat migraine (DTTM) and prior erenumab exposure.

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