Abstract
Purpose: The aim of this study was to evaluate the effectiveness of an educational intervention to improve adherence to Methicillin-Resistant Staphylococcus Aureus control practice among nurses at two Hospitals in Egypt. Methicillin-resistant Staphylococcus aureus (MRSA) is a major pathogen and the most common multidrug-resistant bacterium which is responsible for nosocomial infections, with elevated morbidity and mortality rate. Nurses need a comprehensive intervention to improve adherence to MRSA control practice in order to decrease the rate of its spread.
 Research design: Pre /post-quasi-experimental design was used in this study. This study was carried out at two hospitals in Egypt (Mansoura Chest Disease and Benha University Hospital). A convenient sample of 80 nurses. Tool I- Nurses’s Structured Interview Questionnaire in Arabic language. Tool II - Observational Checklist for MRSA and Infection Control Practice. Descriptive statistics such as frequencies, means, and standard deviations were used to summarize the data. Chi-square and r (correlation) were used to correlate between the studied variables.
 Methodology: Before the application of educational intervention 32.5% of nurses has poor practice levels and the percentage decreased to 7.5%, 14.5 immediately and 2 months post-educational intervention respectively.
 Unique contribution to theory, practice and policy: The educational intervention was effective in improving adherence to Methicillin-Resistant Staphylococcus Aureus control practice among nurses at the two hospitals as there is a statistically significant difference between all phases of the study regarding nurses' practice. Emphasizing the importance of following the latest updated evidence-based approaches to infection control in continuing training programs, and infection prevention with national guidelines (standard precautions) should be provided.
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