Abstract
Molecular medicine is transforming everyday clinical practice from an empirical art to a rational ortho-molecular science. The prevailing concept in this emerging framework of molecular medicine is a personalized approach to disease prevention, diagnosis, prognosis, and treatment. In this mini-review, we discuss the educational and social-ethical issues raised by the advances of biomedical research as related to medical practice; outline the implications of molecular medicine for patients, physicians, and researchers; and underline the responsibilities of academia and the pharmaceutical industry to translate the scientific knowledge to a meaningful improvement of the quality of life across all members of society.
Highlights
[PCR], comparative genomic hybridization, single nucleotide polymorphism arrays) or the transcriptome facilitate optimized, individualized management of patients
The prevailing concept in the emerging framework of molecular medicine is a personalized approach to disease prevention, diagnosis, prognosis, and treatment
While a large body of literature has described multi-gene expression profiles potentially useful for disease classification, diagnosis, and prognosis [5], only a few of these discoveries have been validated independently and fewer are in the process of further development for potential routine clinical use [6]
Summary
[PCR], comparative genomic hybridization, single nucleotide polymorphism arrays) or the transcriptome (real time quantitative PCR, mRNA, and microRNA expression arrays) facilitate optimized, individualized management of patients. The translation of the advances of molecular medicine into clinical practice is not without technical, educational, as well as social-ethical, challenges.
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