EDTA and DTPA modified ligands as sequestering agents for uranyl decorporation

Antoine Leydier,Yi Lin,Guilhem Arrachart,Raphaël Turgis,Delphine Lecerclé,Alain Favre-Reguillon,Frédéric Taran,Marc Lemaire,Stéphane Pellet-Rostaing

doi:10.1016/j.tet.2011.11.065

EDTA and DTPA modified ligands as sequestering agents for uranyl decorporation

Antoine Leydier, Yi Lin + Show 7 more

https://doi.org/10.1016/j.tet.2011.11.065

Copy DOI

Journal: Tetrahedron	Publication Date: Nov 26, 2011
Citations: 23

Affiliation: Institut de Chimie et Biochimie Moléculaires et Supramoléculaires, Claude Bernard University Lyon 1, French National Centre for Scientific Research, Institute for the Separation Chemistry in Marcoule, École Nationale Supérieure de Chimie de Montpellier, University of Montpellier, CEA Marcoule, Atomic Energy and Alternative Energies Commission, CEA Saclay, Institut de Biologie et Technologies

#DTPA Ligands #Chelating Properties + Show 8 more

Abstract
Full-Text PDF
Similar Papers

Abstract

Synthesis of modified EDTA and DTPA ligands and determination of their binding affinities for the uranyl cation are described. Thanks to a screening method, based on a chromophoric complex displacement procedure, chelating properties were studied in aqueous media under various pH conditions for evaluation of their in vivo uranyl-removal efficacy. Each ligand showed a more or less pronounced affinity for uranium. Specific ligands based on EDTA or DTPA analogues containing sulfocatecholamide (CAMS) were found to exhibit a significant affinity towards uranyl ion in acidic, neutral or basic conditions.

Full Text