Abstract
Editors’ pick: re-‘colon’-ization of healthy microbiota after recurrent C. difficile infection
Highlights
The story of Kaitlin Hunter [1] brings to light the potential triumphs of the age of biotechnology and how an understanding of the interplay of genomics and the human microbiome can provide a cure to a life-threatening disease
While a fecal transplant makes logical sense for staving off a C. difficile infection, there are patients who may not opt for such a treatment
Petrof at el. created a stool substitute mixture comprised of a multispecies community no longer in the presence of fecal material
Summary
The story of Kaitlin Hunter [1] brings to light the potential triumphs of the age of biotechnology and how an understanding of the interplay of genomics and the human microbiome can provide a cure to a life-threatening disease. While a fecal transplant makes logical sense for staving off a C. difficile infection, there are patients (and physicians) who may not opt for such a treatment. Petrof et al [3] have devised a solution to ‘RePOOPulate’ the intestines of patients with C. difficile infections.
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