Abstract

Journal of Innovative Optical Health SciencesVol. 12, No. 03, 1902001 (2019) Open AccessEditorialZhen Yuan and Changfeng WuZhen YuanCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, P. R. China and Changfeng WuDepartment of Biomedical Engineering, Southern University of Science and Technology, Shenzhen 518055, P. R. Chinahttps://doi.org/10.1142/S1793545819020012Cited by:0 Next AboutSectionsPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsRecommend to Librarian ShareShare onFacebookTwitterLinked InRedditEmail Cancer including lung cancer, rectal and prostate cancer, colon cancer and breast cancer remains the leading cause of morbidity and mortality worldwide. The use of noninvasive imaging technique to detect cancers at an early stage and achieve image-guided cancer therapy provides better opportunities for patients to obtain effective treatment with fewer side effects. To date, photoacoustic (PA) imaging (PAI) is the fastest-growing area of biomedical imaging technology because PAI enables anatomical, functional and metabolic imaging of tumors with high resolution, high contrast and satisfactory penetration depth. However, the sensitivity of PAI to visualize tumors is determined by its endogenous contrast. By contrast, multifunctional nanoprobes have exhibited their potentials as theranostic agents for PAI-guided cancer theranostics.Interestingly, different multifunctional nanoprobes including inorganic and organic nanoparticles have been developed to improve PAI contrast and enhance cancer efficacy. The inorganic nanoprobes consist of the metal nanoparticles such as the Au and Pd, transition metal dichalcogenides such as the MoS2, WS2 nanosheets and CuS2 nanoparticles, and carbon nanomaterials such as graphene and carbon nanotubes. In addition to inorganic nanoprobes, organic nanoparticles such as BDT-IID based conjugated polymer dots (Pdots) can also serve as multifunctional nanoprobes for enhanced PAI-guided cancer theranostics.This special issue highlights the latest development of inorganic and organic nanoparticles that range from design of multifunctional nanoparticles to PAI and PAI-guided cancer theranostics. The topics for this special issue include but are not limited to:(1)Development of multifunctional nanoparticles for PAI and PA-based multimodal imaging for cancer detection.(2)Development of organic/inorganic nanoprobes for PAI-guided cancer treatment such as phototherapy and immunotherapy.(3)Development of multifunctional nanoprobes for PAI-guided drug/gene delivery and tumor microenvironments monitoring.It is expected that the selected original and review works from this issue can promote the development of multifunctional PA probes for cancer detection and treatment.AcknowledgmentsWe want to take this opportunity to thank the authors and reviewers for their contributions to this special issue. FiguresReferencesRelatedDetails Recommended Vol. 12, No. 03 Metrics History Received 27 May 2019 Accepted 27 May 2019 Published: 30 May 2019 Information© The Author(s)This is an Open Access article published by World Scientific Publishing Company. It is distributed under the terms of the Creative Commons Attribution 4.0 (CC-BY) License. Further distribution of this work is permitted, provided the original work is properly cited.PDF download

Highlights

  • Cancer including lung cancer, rectal and prostate cancer, colon cancer and breast cancer remains the leading cause of morbidity and mortality worldwide

  • Multifunctional nanoprobes have exhibited their potentials as theranostic agents for PAI-guided cancer theranostics

  • The inorganic nanoprobes consist of the metal nanoparticles such as the Au and Pd, transition metal dichalcogenides such as the MoS2, WS2 nanosheets and CuS2 nanoparticles, and carbon nanomaterials such as graphene and carbon nanotubes

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Summary

Introduction

Rectal and prostate cancer, colon cancer and breast cancer remains the leading cause of morbidity and mortality worldwide. Multifunctional nanoprobes for photoacoustic imaging-guided cancer theranostics Zhen Yuan* and Changfeng Wu† *Cancer Center, Faculty of Health Sciences University of Macau, Macau SAR, P. The use of noninvasive imaging technique to detect cancers at an early stage and achieve imageguided cancer therapy provides better opportunities for patients to obtain e®ective treatment with fewer side e®ects.

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