Abstract
The opacity of the peripheral cornea that all persons acquire to some degree in middle life, and occasionally earlier, should be telling us something. The relevant literature in the medical and ophthalmologic periodicals has led to controversial conclusions, possibly because informed and appropriate questions have not always been asked. Histologically and biochemically, arcus corneae — we avoid the term arcus senilis — consists of deposited lipids having a composition similar to that in serum. There is no underlying tissue degeneration nor reactive histiocytosis. Defatted sections, prepared for routine microscopical examination, show normal corneal structure with, ordinarily, no evidence of arcus. . . .
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