Abstract

This special issue of Algorithms is dedicated to approaches to biological sequence analysis that have algorithmic novelty and potential for fundamental impact in methods used for genome research.

Highlights

  • Analysis of high-throughput sequencing data has become a crucial component in genome research

  • Methods based on latest developments in compressed data structures, namely index structures exploiting Burrows-Wheeler transform, are widely deployed in the discovery of disease causing mutations

  • In response to the call for papers, ten articles were submitted to the special issue

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Summary

Introduction

Analysis of high-throughput sequencing data has become a crucial component in genome research. Methods based on latest developments in compressed data structures, namely index structures exploiting Burrows-Wheeler transform, are widely deployed in the discovery of disease causing mutations.

Results
Conclusion
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