Abstract
Editorial: secretion of cytokines and chemokines by innate immune cells.
Highlights
Pulmonary Research Group, Departments of Medicine and Medical Microbiology and Immunology, University of Alberta, Edmonton, AB, Canada
We begin with macrophages, which are best characterized for their ability to transcribe, translate, and process cytokines and chemokines for release [1, 2]
The trafficking machinery required for the secretion of cytokines include soluble NSF attachment protein receptors (SNAREs) and accessory proteins that facilitate membrane fusion, such as GTPases, Munc13, and others
Summary
Pulmonary Research Group, Departments of Medicine and Medical Microbiology and Immunology, University of Alberta, Edmonton, AB, Canada. Cytokines and chemokines are released from a wide range of immune cells, and are essential for the communication of signals in both innate and adaptive immunity. Cytokine and chemokine release by innate immune cells is a fundamental mechanism for cross-talk with the adaptive immune system.
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