Abstract
Editorial: Role of lipids in virus assembly.
Highlights
Specialty section: This article was submitted to Virology, a section of the journal Frontiers in Microbiology
It is established that the nucleocapsid (NC) domain of Gag recognizes motifs in the viral RNA genome to mediate packaging, there is compelling evidence that the matrix (MA) domain binds to cellular RNA to prevent premature Gag targeting to intracellular membranes (Chukkapalli et al, 2010, 2013; Chukkapalli and Ono, 2011; Hogue et al, 2012; Inlora et al, 2014; Kutluay et al, 2014; Olety and Ono, 2014)
Mason-Pfizer monkey virus (M-PMV), which belongs to Betaretroviruses, first assembles into virus-like particles (VLPs) in the pericentriolar region of the infected cell and
Summary
Specialty section: This article was submitted to Virology, a section of the journal Frontiers in Microbiology. This special topic covers key aspects of virus-membrane interactions during assembly and egress of two classes, retroviruses and filoviruses. It discusses molecular mechanisms of assembly and budding of retroviruses and Ebola virus (EBOV) and how various membrane components facilitate these events.
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