Abstract

Editorial: Redox Regulation in Skeletal Muscle Aging and Exercise.

Highlights

  • MRC-Arthritis Research UK Centre for Integrated Research into Musculoskeletal Aging, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK

  • The metabolic and structural changes induced by exercise affect the contractile properties of the muscle fiber

  • An attractive mechanism for the redox regulation of numerous cellular processes is a redox signaling relay from cytoplasmic generation to a mitochondrial response, through the sequential modification of specific residues in regulatory proteins located in close proximity to the sites of endogenously generated ROS/RNS (McDonagh et al, 2014)

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Summary

Introduction

Redox Regulation in Skeletal Muscle Aging and Exercise The species, concentration and cellular location of endogenously generated ROS/RNS can directly and indirectly affect the activity of redox regulated proteins and transcription factors with a multitude of downstream effects. An attractive mechanism for the redox regulation of numerous cellular processes is a redox signaling relay from cytoplasmic generation to a mitochondrial response, through the sequential modification of specific residues in regulatory proteins located in close proximity to the sites of endogenously generated ROS/RNS (McDonagh et al, 2014).

Results
Conclusion

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