Abstract

In his influential book “The Structure of Scientific Revolutions” published in 1962, Thomas Kuhn argued that researchers in every field of scientific enquiry are always guided by theoretical assumptions, presuppositions, and hypotheses that constitute the prevailing scientific paradigm under which they operate at any given time (Kuhn 1962). When they operate within a shared paradigm, a scientific community working in a particular field will be committed to using certain strategies and experimental approaches that are accepted as being essential for trying to solve the problem at hand.

Highlights

  • CNRS, UMR 7242 Biotechnologie et Signalisation Cellulaire, Institut de Recherche de l’Ecole de Biotechnologie de Strasbourg (IREBS), Ecole Supérieure de Biotechnologie Strasbourg (ESBS), University of Strasbourg, Illkirch, France

  • In his influential book “The Structure of Scientific Revolutions” published in 1962, Thomas Kuhn argued that researchers in every field of scientific enquiry are always guided by theoretical assumptions, presuppositions, and hypotheses that constitute the prevailing scientific paradigm under which they operate at any given time [1]

  • When they operate within a shared paradigm, a scientific community working in a particular field will be committed to using certain strategies and experimental approaches that are accepted as being essential for trying to solve the problem at hand

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Summary

Introduction

CNRS, UMR 7242 Biotechnologie et Signalisation Cellulaire, Institut de Recherche de l’Ecole de Biotechnologie de Strasbourg (IREBS), Ecole Supérieure de Biotechnologie Strasbourg (ESBS), University of Strasbourg, Illkirch, France. When past mistakes are acknowledged can novel paradigms be introduced, which better fit our improved knowledge of HIV-1 immune responses, and are more likely to help future vaccine development [4, 5].

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