Abstract
Editorial: Lipid Signaling in T Cell Development and Function.
Highlights
Best known as energy storing molecules and core-components of cellular membranes, lipids are important regulators of cell signaling
Non-covalent membrane lipid interactions control the mechanics of T cell receptor (TCR) signal transduction [3, 4]
Membrane lipids can act as secondmessengers, as exemplified by the phosphoinositide-3-kinase (PI3K) lipid-product phosphatidylinositol[3,4,5]trisphosphate (PIP3) in lymphocytes, the topic of several reviews here, and of a recent dedicated Research Topic in Frontiers in Immunology [5]
Summary
Best known as energy storing molecules and core-components of cellular membranes, lipids are important regulators of cell signaling. Non-covalent membrane lipid interactions control the mechanics of T cell receptor (TCR) signal transduction [3, 4]. Membrane lipids can act as secondmessengers, as exemplified by the phosphoinositide-3-kinase (PI3K) lipid-product phosphatidylinositol[3,4,5]trisphosphate (PIP3) in lymphocytes, the topic of several reviews here, and of a recent dedicated Research Topic in Frontiers in Immunology [5].
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