Abstract

Editorial: Improving cancer chemotherapy through pharmacogenomics: a research topic.

Highlights

  • Specialty section: This article was submitted to Pharmacogenetics and Pharmacogenomics, a section of the journal Frontiers in Genetics

  • It is well known that the efficacy and safety of chemotherapeutic drugs show substantial individual and/or population variability that can be explained, to a great extent, by genetic factors in pharmacokinetics and pharmacodynamics (Quiñones et al, 2008; Roco et al, 2012; Izar et al, 2013; Kessler et al, 2014; Patel, 2015; Unger et al, 2015)

  • Pharmacogenomics is an emerging field focused on genetic variations relevant to drug action (Evans and Relling, 2004; Maxmen, 2011; Mayer, 2014; Zhou et al, 2015)

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Summary

Introduction

Specialty section: This article was submitted to Pharmacogenetics and Pharmacogenomics, a section of the journal Frontiers in Genetics. Editorial: Improving cancer chemotherapy through pharmacogenomics: a research topic. It is well known that the efficacy and safety of chemotherapeutic drugs show substantial individual and/or population variability that can be explained, to a great extent, by genetic factors in pharmacokinetics and pharmacodynamics (Quiñones et al, 2008; Roco et al, 2012; Izar et al, 2013; Kessler et al, 2014; Patel, 2015; Unger et al, 2015).

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