Abstract
On 15 September 2022, Science published the Research Article “Structural basis for strych-nine activation of human bitter taste receptor TAS2R46” by Weixiu Xu et al. (1). The editors have been made aware that the examination of data provided after publication revealed potential discrepancies with fig. S10D. This figure was used to support a proposal of precoupling between TAS2R46 and the G protein gustducin. We are alerting readers to these concerns while the authors’ institution investigates further.
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