Abstract
Editorial: Determinants of Synaptic Information Transfer: From Ca(2+) Binding Proteins to Ca(2+) Signaling Domains.
Highlights
Ca2+ ions are key regulators of fundamental synaptic processes including transmitter release and the induction of plasticity. They act within complex topographical relationships between the sites of Ca2+ influx and those sites where the Ca2+ controlled effector proteins are located. These topographies are dynamically shaped by protein-complexes and the spatio-temporal extent of Ca2+ elevations within these topographies is controlled by Ca2+ buffers
Synaptic information transfer begins with presynaptic transmitter release
A synapse that operates with nano-domain influx-release coupling is the parallel-fiber (PF) to Purkinje cell (PC) synapse
Summary
Ca2+ ions are key regulators of fundamental synaptic processes including transmitter release and the induction of plasticity. Editorial: Determinants of Synaptic Information Transfer: From Ca2+ Binding Proteins to Ca2+ Signaling Domains (2016) Editorial: Determinants of Synaptic Information Transfer: From
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