Abstract
Editorial: Current Challenges in Immune and Other Acquired Cytopenias of Childhood.
Highlights
The Editorial on the Research Topic Current Challenges in Immune and Other Acquired Cytopenias of Childhood
Chronic immune thrombocytopenia (ITP), Evans syndrome (ES), aplastic anemia, etc., are descriptive terms for immune-mediated cytopenias in pediatric hematology that may be summarized as a group of disorders of immune dysregulation based on ill-defined poly- and epigenetic diatheses toward autoimmunity and monogenic primary immunodeficiencies (PIDs); a growing number of which is being identified with next-generation sequencing technologies
The indication for stem cell transplantation will always predominantly depend on the clinical course and status of a patient, the definition of a clear-cut pathomechanism potentially offers a guidance toward targeted therapy approaches
Summary
The Editorial on the Research Topic Current Challenges in Immune and Other Acquired Cytopenias of Childhood. Chronic immune thrombocytopenia (ITP), Evans syndrome (ES), aplastic anemia, etc., are descriptive terms for immune-mediated cytopenias in pediatric hematology that may be summarized as a group of disorders of immune dysregulation based on ill-defined poly- and epigenetic diatheses toward autoimmunity and monogenic primary immunodeficiencies (PIDs); a growing number of which is being identified with next-generation sequencing technologies.
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