Abstract
EDITORIAL article Front. Endocrinol., 28 August 2015Sec. Experimental Endocrinology Volume 6 - 2015 | https://doi.org/10.3389/fendo.2015.00132
Highlights
White adipose tissue is responsible for the secretion of an array of signaling molecules, termed adipokines that function as classic hormones in other target tissues and whose secretion is affected by metabolic dysregulation [1]
Adipose tissue has the capacity to grow by hyperplasia through formation of new adipocytes from precursor cells and by hypertrophy of existent adipocytes [2], which is essential for the correct function of the cell and metabolic control, and can be altered in different pathologies, such as obesity
It is considered that obesity-induced insulin resistance results, at least in part, from an imbalance in the secretion of pro- and anti-inflammatory adipokines, which are reviewed in this manuscript
Summary
White adipose tissue is responsible for the secretion of an array of signaling molecules, termed adipokines that function as classic hormones in other target tissues and whose secretion is affected by metabolic dysregulation [1]. Adipose tissue has the capacity to grow by hyperplasia through formation of new adipocytes from precursor cells and by hypertrophy of existent adipocytes [2], which is essential for the correct function of the cell and metabolic control, and can be altered in different pathologies, such as obesity. Pessin and Kwon [3] examine the recent progress regarding the physiological and molecular functions of adipokines in obesity-induced inflammation and insulin resistance.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
