Abstract
In this single-center study, Giannarini et al. prospectively evaluated the sensitivity values and false detection rates (FDRs) achieved by 2 experienced readers using the Prostate Imaging Reporting and Data System, version 2 (PI-RADS v2), for the detection of clinically significant cases of prostate cancer (PCa). The study included 48 patients who underwent 3 Tesla multiparametric magnetic resonance imaging (MRI) without endorectal coil before undergoing radical prostatectomy (RP). Whole-mount RP specimens were used as the reference standard, and clinically significant PCa was defined as tumors with any of the following characteristics: dimension ≥1 cm; International Society of Urological Pathology Grade Group ≥2; and pathologic stage ≥T3. As a secondary outcome, the authors also assessed the inter-reader agreement.
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