Abstract
The need or benefit of cold ischemia during renal hilar clamping for partial nephrectomy for renal cell cancer (RCC) remains controversial, and the results from various series are inconsistent. The topic is clouded further by uncontrolled comparisons between minimally invasive surgery with warm ischemia and open surgery with cold ischemia. Among the uncontrolled biases are case selection, surgeon experience, duration of clamping, tumor complexity, and variable renal function at baseline. To the authors' credit, the present study1 presents a prospective, randomized 1:1 comparison of open partial nephrectomy for clinical stage T1 RCC in 60 patients each with either warm ischemia or cold ischemia.
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