Editorial Comment on “Penile Prosthesis Implantation in Patients With Peyronie's Disease: Results of the PROPPER Study Demonstrate a Decrease In Patient-Reported Depression”

Abstract

Peyronie's disease (PD) has a significant impact on quality of life. Severe erectile dysfunction (ED) coexists with PD in approximately 30% of cases, and in these men, a well-established treatment option is insertion of an inflatable penile prosthesis (IPP).1 This procedure is safe, associated with a high degree of patient satisfaction, and is capable of achieving curvature correction in a large percentage of patients.2 The current state of the literature is lacking with regard to interactions among PD, ED, and depressive symptomology. Given this, the authors of the associated brief communication3 sought to establish a correlation between depression and men with concurrent PD and ED after insertion of an IPP. The study used the PROPPER (Prospective Registry of Outcomes with Penile Prosthesis for Erectile Restoration) database of a large cohort of men with and without PD. This very robust dataset, as analyzed in the study, examined 1,180 men enrolled from June 2011 through February 2016.3 Unfortunately, the conclusions drawn are hampered by the imperfect nature of the information within the dataset.