Editorial Comment from Dr Ishizuka to Effect of intrathecal administration of E‐series prostaglandin 1 receptor antagonist in a cyclophosphamide‐induced cystitis rat model

Abstract

ganglia. J. Neurochem. 1991; 57: 167–74. 14 Hu VY, Malley S, Dattilio A et al. COX-2 and prostanoid expression in micturition pathways after cyclophosphamide-induced cystitis in the rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2003; 284: R574–85. 15 Schroder A, Newgreen D, Andersson KE. Detrusor responses to prostaglandin E2 and bladder outlet obstruction in wild-type and EP1 receptor knockout mice. J. Urol. 2004; 172: 1166–70. 16 Chuang YC, Yoshimura N, Huang CC et al. Expression of E-series prostaglandin (EP) receptors and urodynamic effects of an EP4 receptor antagonist on cyclophosphamide-induced overactive bladder in rats. BJU Int. 2010; 106: 1782–7. 17 Minami T, Nishihara I, Uda R et al. Characterization of EP-receptor subtype involved in allodynia and hyperalgesia induced by intrathecal administration of prostaglandin E2 to mice. Br. J. Pharmacol. 1994; 112: 735–40. 18 Uda R, Horiguchi S, Ito S et al. Nociceptive effects induced by intrathecal administration of prostaglandin D2, E2, or F2 alpha to conscious mice. Brain Res. 1990; 510: 26–32. 19 Malmberg AB, Rafferty MF, Yaksh TL. Antinociceptive effect of spinally delivered prostaglandin E receptor antagonist in the formalin test on the rat. Neurosci. Lett. 1994; 173: 193–6. 20 Miura A, Kawatani M, Maruyama T et al. Effect of prostaglandins on parasympathetic neurons in the rat lumbosacral spinal cord. Neuroreport 2002; 13: 1557–62.