Abstract
Editorial: At the top of the interneuronal pyramid-calretinin expressing cortical interneurons.
Highlights
Intracellular protein calretinin (CR) acquired its name based on structural similarity to calbindin D28k and the site of first detection—retina (Rogers, 1987)
In the Research Topic “At the top of the interneuronal pyramid—calretinin expressing cortical interneurons,” we intended to provide a summary of current knowledge on CR+ cortical neurons and especially to emphasize and discuss those “unique features” of CR+ neurons mentioned above
Further two original research papers focus on the development of CR+ neurons during the ontogenesis of human cerebral cortex
Summary
Intracellular protein calretinin (CR) acquired its name based on structural similarity to calbindin D28k and the site of first detection—retina (Rogers, 1987). While extensive literature on PV expressing (PV+) interneurons’ physiological functions and changes in various pathological conditions have been published, we still have a limited view about the CR+ (and CB+) interneurons. In the Research Topic “At the top of the interneuronal pyramid—calretinin expressing cortical interneurons,” we intended to provide a summary of current knowledge on CR+ cortical neurons and especially to emphasize and discuss those “unique features” of CR+ neurons mentioned above.
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