Abstract

Editorial: Adrenal Cortex: From Physiology to Disease

Highlights

  • UMR6293 GReD, Molecular Pathophysiology of Adrenal and Endocrine Tissues, CNRS, Aubiere, France Keywords: adrenal, development, physiology, zonation, disease, benign tumour, cancer, insufficiency

  • The coordinate production of these steroids relies on adrenal cortex zonation, which corresponds to the establishment of distinct concentric functional zones in the perinatal period: outermost zona glomerulosa synthesizes mineralocorticoids, zona fasciculata produces glucocorticoids, and innermost zona reticularis synthesizes both glucocorticoids and adrenal androgens

  • The review by Pihlajoki et al summarizes the latest findings on the mechanisms of adrenal cortex renewal, which relies on outer cortex progenitors recruitment and lineage conversion along cell migration within the cortex

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Summary

Introduction

UMR6293 GReD, Molecular Pathophysiology of Adrenal and Endocrine Tissues, CNRS, Aubiere, France Keywords: adrenal, development, physiology, zonation, disease, benign tumour, cancer, insufficiency. Editorial: adrenal Cortex: From Physiology to disease The Editorial on the Research Topic Adrenal cortex: from physiology to disease

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