Abstract
There is certainly no panacea to the manifest problems of neurodegeneration, but in their fascinating article, Tom Prolla and Mark Mattson discuss the surprisingly dramatic effects observed in rats fed on a diet where the energy intake is 70% of normal (see pages S21–S31). These animals have vastly improved lifespans, retain the physiology of young animals for longer and might have increased resistance to ND; an interesting irony given the rising levels of obesity in modern society.And so I hope you will enjoy the articles in this special issue, and please remember to visit Trends in Neurosciences regularly for its continued coverage of this field and fresh insights into research advances as they occur.
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